공지사항

재능마켓 Today’s CSIR-Indian Institute of Chemical Biology was germinated as Indian Institute of 마케팅 서비스 Medical Research in 1935 in central Calcutta. A group of highly talented 무료콜백문자 biomedical scientists propelled by the Nationalistic feeling catapulted themselves in the orbit 원격 컴퓨팅 of basic understanding of tropical diseases ravaging our country in those days. 마케팅기업 The organization was unique is being the only basic biomedical research centre 영업문자 in the country started without any pecuniary assistance from the Empire.In due 개발업체 course, the institute set about untangling various health related objectives which provided 앱솔루션 a crucial base from where the present institute has grown. Despite the 어플제작 financial difficulties at the early stage, the intensity of creative and fertile 채팅솔루션 scientific enterprise got of a good start as evident from a number 개발회사 publications in the journal Nature. After a span of so many years 콜백문자 through a cursory glance, it is not easy to window the agonies 마케팅프로그램 and ecstasies of those dedicated souls.  Out of infectious diseases prevalent in our 프로그램 스토어 country in those days, studies on the biology of cholera bacteria and 챗솔루션 vaccine development were a priority. Cholera was originally endemic to the Indian 마케팅 프로그램 subcontinent, with the Ganges River likely serving as a source of contamination. 일반채팅 It was largely due to pioneering efforts of Dr. Sachimohan Mukherjee, the 앱부스터 cholera research gained momentum. Dr. Mukherjee’s early interest was on the cholera 앱마케팅 phage, the virus that can infect V. cholerae and kill the bacteria. 스마트폰콜백 He developed highly successful new phage typing scheme for V. cholerae. Using 가상 윈도우 this technique he showed that V. cholerae strains responsible for yearly epidemics 앱개발 in Bengal can be categorized into several types. Cholera phage typing was 몽키VPN accepted as one of the most reliable technique for epidemiological characterization of 게임 VPN V. cholerae strains (Ann. Biochem. Exp. Med. 1962, 22, 9-12) This simple 앱스토어 검색 technique offered a useful tool to follow the route by which infections 자동콜백 travelled to distant places of endemic foci. The institute gained international acclaim APP 개발회사 for this new discovery and World Health Organization set up a reference 채팅어플 laboratory in this institute.Dr. Mukherjee’s vision and deep understanding of the cholera 아이피 변경 disease biology led him to realize the advantage of an oral cholera 화상채팅 vaccine. The possibility of developing a live oral cholera vaccine with an 온라인 마케팅 avirulent culture of an El Tor vibrio strain isolated from a water 게임IP source in Calcutta has been studied by his group. Detailed laboratory studies VPN on the antigenic composition, pathogenicity and immunogenic value of the apparently apathogenic 마케팅IP El Tor strain was studied at length. In animal studies it was 앱개발 shown that the vaccine strain was capable of multiplication in the gastrointestinal 마케팅 VPN tract of rabbits and gives rise to antibacterial as well as to 플레이스토어 검색 antitoxic immunity. A trial was initiated to examine the safety and immunogenicity 콜백문자서비스 of the proposed vaccine in humans.The trial was carried out on 25 채팅앱개발 human volunteers from members of the staff of the Institutemost of them 영업 had not had occasion to handle cholera cultures in the laboratory. Each 자동문자 dose of vaccine was administered on an empty stomach and no food 프로그램스토어 was allowed to the volunteers within 2 hours of an administration of 마케팅 전문가 vaccine. There was evidence that live vibrios were present throughout the intestinal 마케팅프로그램 tract although no untoward effect was produced in any of the volunteers. 프로그램 This was reasonable proof that the proposed vaccine is safe for human VPN use. In spite of 2 successive passages through the human intestine there DB추출기 was no change in the pathogenicity of the strain. Therefore, there was 마케팅 스토어 little likelihood of the emergence of a virulent strain after such vaccination.After 문자명함 live oral cholera vaccination, the volunteers developed both humoral and copro-antibodies (antibodies NEW DB in faeces) which indicates a status of immunity of the vaccinated individuals. 마케팅프로그램 After one course of vaccination, consisting of 2 weekly doses, the antibody 마케팅스토어 titre in blood appears to last for at least 6 months. On VPN 서비스 the other hand, the local antibodies in the form of free faecal 가상 컴퓨터 antibodies or antibodies present in the cells of the mucous membrane of 가상 윈도우 컴퓨터 the intestinal tract are likely to play a more significant role in 스마트문자 protection against the infecting organism. Most of the volunteers showed by the 채팅어플제작 tests adopted, the presence of copro-antibodies in low titre within a short 영업디비 time after live oral vaccination and they continued to show the presence 실행사 of these copro-antibodies. The present findings indicate that the live oral cholera VPN 서비스 vaccine consisting of an avirulent El Tor culture was safe for human DB프로그램 use and is likely to give rise to both local and systemic antibodies (Bull. Wid. Hlth. Org 1959, 40, 503-511).The concept that live oral cholera vaccine is possible, was shown by Dr. Sachimohan Mukherjee of this institute for the first time and opened up new avenues of further research.Arun BandyopadhyayDirector, CSIR-IICB