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Mesothelioma - what causes pericardial mesothelioma causes peritoneal mesothelioma - Recommended Web page, Causes Mesothelioma?
As with all cancers mesothelioma symptoms are similar to those of other cancers. Early diagnosis and treatment can enhance the chance of a patient being diagnosed. Asbestos is the most significant cause of mesothelioma. Asbestos is made up of minerals in a group which can be split into thin, long fibres. When inhaled or consumed, the asbestos fibres can get stuck in the lining of certain organs. Exposure to Asbestos Exposure to asbestos is the most confirmed cause of Mesothelioma. Asbestos, a naturally occurring mineral, is composed of strong and microscopic fibers. It was extensively used in automobiles, buildings, and a variety of construction equipment from the 1930s until the early 1980s because it resisted fire, water and sound. The makers of asbestos-based materials were aware of the dangers it poses to health, yet they did not inform the public. Workers who directly handled asbestos or handled products made from it were at greatest risk of being exposed. Mining and shipbuilding, asbestos removal and other industrial jobs exposed workers to large amounts of asbestos. The workers also had to be exposed to asbestos-containing products, including shingles, pipes, glues and talcum powder. Chrysotile asbestos is the most widely used type of asbestos in the United States. However, other kinds of asbestos, including amosite and crocidolite, also have been linked to mesothelioma. Mesothelioma symptoms typically do not appear until decades after exposure to asbestos. Once they do, [Redirect-302] the disease can quickly progress and eventually become fatal. The symptoms are most commonly seen in the lungs (pleural mesothelioma) but they can also affect the stomach's lining or the testicles. When asbestos fibers are swallowed or inhaled they adhere to cells that connect the body's organs and tissues. This causes genetic mutations that can lead to cancer. Mutated cells multiply uncontrollably and form tumors. Workers in industries that are exposed to asbestos more often are at a greater risk of developing mesothelioma. Those at greatest risk are those who worked in blue-collar jobs or were in the military. Women who have been exposed to asbestos can develop mesothelioma. This is especially true if their family members were exposed at work. Secondary exposure can happen when someone who is at risk of mesothelioma wears asbestos-containing fibres on their clothing and other clothing. This has happened to spouses of asbestos exposed people, as well as some tile and hairdressers. Certain studies have shown that a mineral like asbestos, erionite, increases the risk of mesothelioma causes, however this has not been proven elsewhere. Exposure to Minerals Mesothelioma results from the transformation of cells that line certain areas of the body, including the lining of the chest (pleura) and abdominal cavities. Mesothelioma can also occur in the lining of the heart (pericardium) or testicles (tunica vaginalis). The condition is usually associated with asbestos exposure, but other causes can also be the cause. Asbestos is a naturally occurring mineral made up of strong microscopic fibers. It was used for building material, in brakes for automobiles, and for a variety other products in the 1930s and 1980s because it was resistant to fire, water and sound. A lot of people working in the construction industry or military were exposed. Workers who handle and remove asbestos are at a higher risk of inhaling the hazardous particles. Although the exact mesothelioma risk varies by job, any type of asbestos exposure increases the likelihood of developing the disease. Mesothelioma is associated with a wide range of jobs, but it more typically affects miners, millers and shipyard workers and asbestos producers. It has also been discovered in those who worked on the manufacturing of automobiles and aircraft, as well as those who handled or sanded insulation. Mesothelioma is usually diagnosed slowly, however symptoms can be noticed between 20 and 60 years after asbestos exposure. Even if you've never been exposed to asbestos, it's crucial to talk to your doctor regarding mesothelioma. The earlier cancer is detected the easier it is to treat it successfully. In the past, many who were diagnosed with mesothelioma didn't be diagnosed until their condition had progressed. Mesothelioma is a rare form of cancer, which is why doctors often overlook the signs such as a persistent cough or difficulty breathing. Asbestos was eliminated in the 1980s. However, those who worked in the military or in the industrial sector prior to that time are still at higher risk of developing mesothelioma. Researchers have recently discovered other types of exposure to mineral that increase mesothelioma risks. In Turkey for instance the mineral known as Erionite is present in the soil and used to make materials. In studies of the local population that is exposed to erionite in a high degree the risk for men is higher than women to develop mesothelioma. The same is the case with another mineral called fluoro-edenite in Italy. Genetics Mesothelioma is a form of cancer that affects the mesothelium. It is most common in the lining of the chest cavity (pleura) however it also can affect tissue around the abdomen, the heart and the testicles. Doctors have linked mesothelioma to a mutation in the gene called BAP1. This gene regulates a process which puts calcium in cells, and when it's mutated the person is mesothelioma always caused by asbestos more likely to develop cancerous cells. Researchers have discovered that BAP1 mutations are found in 70 percent of patients with mesothelioma. This discovery has made mesothelioma more easy to recognize and has led to increased screening, especially for those with an ancestral history. Researchers have also identified other genetic mutations which may lead to mesothelioma development. These mutations have made it easier for mesothelioma specialists to better know the disease and treat it more effectively. While genetics can play a role in mesothelioma, asbestos is still the primary risk factor for the cancer. Certain asbestos-exposure victims do not develop cancer, but others with no genetic predisposition could develop mesothelioma during a lengthy period of exposure. Secondary exposure, or paraoccupational exposure, can a single exposure to asbestos cause mesothelioma occur when asbestos-exposed colleagues bring home fibers that are absorbed into their clothing and skin. In some cases mesothelioma is seen to run in families because of a combination of genetics and asbestos exposure. However, the majority of mesothelioma patients are random and do not appear to have any family histories of the disease. Asbestos-related mesothelioma is a severe and complicated disease, but research continues to make remarkable advancements in treatment and recovery options for patients. Asbestos is now banned in a number of countries across the globe and researchers are advancing mesothelioma treatments by utilizing better drugs, more specific surgeries, and more efficient diagnostic tests. To find out more about these latest advances you can request a copy of the Mesothelioma Guide. This comprehensive resource includes the complete list of mesothelioma treatments and treatments, including the most recent clinical trials as well as promising alternative therapies. Download the guide by filling in our online form or by calling directly. Enjoy the Life you live Mesothelioma is a cancer that affects the cells that line certain parts of the body, including the abdomen or lungs. The the lining of your chest cavity (the Pleura) is where the majority of cases of mesothelioma begin. However, it may also begin in the lining of the heart and abdomen (the Pericardium). While asbestos exposure is a primary risk factor but other factors, such as age or gender can increase the chance of developing mesothelioma. Some of these factors such as smoking or a person's gender can be altered, whereas others, such as age or family history, cannot. Most mesothelioma patients are related to someone else who has the disease and have been exposed to asbestos for a long period of. The majority of patients diagnosed with peritoneal or pleural cancer are older than 45. This is because mesothelioma takes many years to develop and symptoms may begin to show as a person grows older. A biopsy is among the tests used by doctors to determine if pleural mesothelioma is present. Other tests include the CT scan, FDG-positron emission tomography and a CT scan. A biopsy is the process of removing some of the tissue to examine under a microscope, and can be done by using VATS (Video-assisted surgery using thoracoscopic instruments), a type of keyhole procedure; or a needle guided by the CT scan. Doctors can test blood for a genetic variant called BAP1. This is a mutation in the gene that inhibits the growth of tumors and makes a person more susceptible to developing malignancies caused by environmental contaminants. This mutation increases the chance of developing mesothelioma, even after relatively low levels asbestos exposure. It also reduces the time to develop mesothelioma for those who have this mutation. Researchers do not know yet how much asbestos can cause mesothelioma common this mutation in the general public is or if it is prevented through lifestyle choices such as avoiding toxic substances. This is a research area that is ongoing. |
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