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Mesothelioma - What Causes Mesothelioma?

As with all cancers, mesothelioma's symptoms may be similar to those of other cancers. However, early diagnosis and treatment can improve a patient's prognosis.

Asbestos exposure is a major reason for mesothelioma. Asbestos is one of the minerals that are able to break down into long, thin fibers. Asbestos fibres can become stuck in certain organs when inhaled or consumed.

Exposure to Asbestos

The most proven reason for mesothelioma is exposure to asbestos. Asbestos is a naturally occurring mineral that consists of strong, microscopic fibers. It was widely employed in vehicles, buildings and a variety of other construction products between 1930s and the beginning of the 1980s because it was invulnerable to fire, water, and sound. The manufacturers of asbestos-based products were aware about its health risks, but did not tell the public.

Those who worked directly with asbestos or handled products made from it were most at risk of exposure. Mining and shipbuilding, asbestos removal and other causes of mesothelioma industrial jobs exposed workers to large amounts of asbestos. Asbestos-containing products such as shingles, pipes and glues, as well as the talcum powder, were utilized at home by those who were also exposed. In the United States, chrysotile asbestos is the most frequently used. However, other types of asbestos, including amosite and crocidolite, also have been linked to mesothelioma.

Symptoms of mesothelioma usually are not evident for a long time after asbestos exposure. When they do, the disease can grow rapidly and eventually cause death. Symptoms most often affect the lung (pleural mesothelioma) however, they can also manifest in the stomach's lining and testicles, or in the heart.

Asbestos fibres inhaled or consumed stick to the cells that line internal organs and tissues. This causes genetic mutations that result in cancer. The cancerous cells expand uncontrollably, and eventually form tumors.

Workers in industries that are exposed to asbestos more often have a higher chance of developing mesothelioma. Those at greatest risk are men who had blue-collar jobs or were in the military. However, mesothelioma can develop in women who were exposed to asbestos, in particular when they cared for family members exposed to asbestos while at work.

Secondary exposure can happen when someone at the risk of developing mesothelioma wears asbestos-containing fibres on their clothing and clothes. This has been reported to spouses of asbestos-exposed people as well as hairdressers and tile workers. Certain studies have demonstrated that a mineral called Erionite, a mineral that is similar to asbestos, may increase the risk of developing mesothelioma. However it has not been confirmed by other studies.

Exposure to Minerals

Mesothelioma develops from the transformation of cells that line certain areas of the body, including the lining of the chest (pleura) and abdominal cavities. Mesothelioma may also develop in the linings of the heart (pericardium), or testicles. The disease is most commonly caused by exposure to asbestos, however there are other causes of mesothelioma other than asbestos.

Asbestos is a natural mineral made up of strong, microscopic fibers. It was utilized in building materials, automobile brakes, and various other products from the 1930s through the 1980s, due to its resistance to water, fire, and sound. Many workers employed in the construction industry or military were exposed. Workers who handle and remove asbestos are at greater risk of inhaling the dangerous particles.

While the risk of mesothelioma varies by job, any asbestos exposure increases a person's likelihood of developing the disease. Mesothelioma is associated with many different occupations, but it most often is a problem for miners, millers and shipyard workers and asbestos manufacturers. It has also been discovered among those working on the production of automobiles or aircraft and also in those who handled or processed insulation.

Mesothelioma typically develops slowly, but symptoms can appear 20 to 60 years after exposure to asbestos. Even if you've never worked with asbestos, it's crucial to talk to your doctor regarding mesothelioma. The earlier the cancer is identified, the easier it is to treat successfully.

In the past, mesothelioma could not be discovered until it had grown. Mesothelioma is a rare form of cancer, and doctors often overlook the signs such as a persistent cough or breathing difficulties.

Asbestos was eliminated by the 1980s. However those who worked in the military and in the industrial sector before the time were still at a higher risk of mesothelioma. Researchers have recently discovered different types of mineral exposure which increase the risk of mesothelioma. For example, a mineral called erionite can be found in the soil of a few regions in Turkey and is used to make materials that are used in the production of materials. In studies of the local population that is exposed to erionite extensively the risk for men is mesothelioma always caused by asbestos - whatismesotheliomacausedb19097.suomiblog.com explains, higher than women to develop mesothelioma caused by radiation. In Italy the same phenomenon has been observed in relation to another mineral known as fluoroedenite.

Genetics

Mesothelioma is a type of cancer that affects the mesothelium. It is typically located in the lining of the chest cavity, but can also affect the tissue around the abdomen, heart and the testicles.

Doctors have linked mesothelioma with the mutation in the gene known as BAP1. This gene regulates a process that puts calcium in cells, and when it is mutated, a person is much more likely to develop cancerous cells. Researchers have discovered that BAP1 mutants are present in 70 percent of patients with mesothelioma. This discovery has made it easier for doctors to identify mesothelioma, and to increase screening for the disease, particularly in people who have an asbestos-related family history. exposure.

Researchers have also identified additional genetic mutations which may cause mesothelioma development. These mutations have made it easier for mesothelioma specialists to better understand the disease and better treat it.

While genetics can influence mesothelioma however asbestos is the leading risk factor for the cancer. Certain people who are exposed to asbestos do not develop cancer, whereas others who have no genetic predisposition develop mesothelioma over a long period of time in exposure. Paraoccupational or secondary asbestos exposure can be a result of coworkers who have been exposed to asbestos carry fibers to their clothing and skin.

In some cases mesothelioma can be found in families due to a combination of genetics as well as asbestos exposure. Most mesothelioma appears to be a random disease and doesn't appear to have any family history.

Asbestos-related mesothelioma is a serious and complex disease, however research continues to make incredible advancements in treatment and recovery options for patients. Asbestos has been banned in a number of countries, and scientists are striving to improve treatment for mesothelioma by using better drugs, more targeted surgeries and a more efficient diagnostic test. Download a free copy our Mesothelioma Guide to learn about the ways these new developments could help you. This comprehensive guide provides a complete listing of mesothelioma treatment options that include the most up-to-date clinical trials and promising options. The guide is available for download by completing our brief, Is Mesothelioma Always Caused by Asbestos online form or calling us directly.

Lifestyle

Mesothelioma is a cancer that affects the cells that line certain areas of the body, such as the lungs or abdomen. The majority of cases of mesothelioma begin in the lining of the chest cavity (the pleura), but it can also occur in the lining of the abdomen (the peritoneum) and around the heart (the pericardium).

While asbestos exposure is a major risk factor however other factors like gender and age can a single exposure to asbestos cause mesothelioma also increase the likelihood of developing mesothelioma. Certain of these factors like smoking, or a person's gender can be changed, while others, such as age or family history, are not.

Most people with mesothelioma are related to someone else who has the disease and who has been exposed to asbestos for a lengthy period of. Most people diagnosed with pleural or peritoneal cancer are older than 45. This is due to the fact that mesothelioma can take decades to develop and the symptoms can begin to appear as an individual ages.

There are several tests that doctors use to diagnose mesothelioma, including a CT scan (computerised tomography) or FDG-positron emission (a test that makes use of the use of a radioactive substance to determine the extent of the tumor's growth) and a biopsy. A biopsy is the process of removing a small amount of tissue for examination under a microscope. It can be done using VATS (Video-assisted thoracoscopic surgery) which is a kind of keyhole surgery; or a needle guided by the CT scan.

Doctors can also test a patient's blood for a genetic defect called BAP1. This is an error in the gene responsible for reducing the growth of tumors and makes one more prone to developing cancers caused by environmental toxins. People with this mutation are more likely to develop mesothelioma when they have experienced relatively low levels of exposure to asbestos, and they have an earlier time of onset than those who do not have the genetic mutation. Researchers do not know yet the extent to which this mutation is prevalent in the general population or if it can be prevented by lifestyle choices such as avoiding toxic substances. This is an area of ongoing research.