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Myelodysplastic Syndrome

MDS occurs when the stem cells found in bone marrow have been damaged and produce too many red cells. The condition can lead to anemia, and then progress to acute leukemia in a third of patients.

myelodysplastic syndrome mds Syndrome has been associated with exposure to benzene. This chemical is used in the production of railway products, such as Safety-Kleen and other solvents. A former machine operator developed the disease after years of exposure to benzene at work.

Causes

MDS affects the bone marrow. This is the spongy part of your bones where blood cells are produced. When you suffer from MDS, your bone marrow produces abnormal stem cells that fill the bone marrow and prevent it from producing enough normal blood cells. Blood cells are vital to keep you healthy, because they carry oxygen, fight infection and stop bleeding through clotting. If you suffer from MDS you could develop low blood cell counts (anemia), easy bruising and bleeding, as well as frequent infections.

MDS can be subdivided depending on the type of blood cell affected. There are two kinds of MDS that are: 1.) single-lineage dysplasia, which causes a particular type of blood cell to be deficient; and) multilineage dysplasia, which causes more than one blood cell type to be low.

A number of factors could increase your risk of myelodysplastic disorder, including age, genetics, and myelodysplastic Syndrome mds exposure to certain chemicals. Benzene, an extremely well-known cancerous compound, has been linked with Myelodysplastic Syndrome lawsuit settlements disorder. Railroad workers exposed to benzene in the course of the job may be at a higher risk of contracting this disease.

Chemicals such as trichloroethylene (perchloroethylene) ammonia and trichloroethylene can increase your risk of developing Myelodysplastic syndrome Mds syndrome. Solvents such as these are used to degrease metal components in industrial settings. Many rail workers, such as track department employees as well as locomotive machine operators, are exposed to these chemicals on a regular basis.

Signs and symptoms

In a healthy person the bone marrow produces blood cells that mature to become red blood cells, platelets and white blood cells. The three types of blood cells have different roles: red blood cells transport oxygen while white blood cells guard against infection and platelets help in stopping bleeding by clotting. In MDS the blood cells that are immature develop abnormally and do not fully function. In the end blood counts decrease and symptoms like weakness, fatigue and even easy bleeding can occur.

MDS is classified into subtypes based on the type of abnormal blood-cell involved. A subtype called single-lineage Myelodysplastic Syndrome railroad injury dysplasia, as an example, has low numbers of a particular blood cell type. Another type of myelodysplastic that has sideroblasts in the ring is a mixture of blood cell types.

Benzene is a leading cause of MDS. Railroad workers who used products like fuels, thinners, mineral spirits paints and degreasers were exposed to benzene on a regular basis. Diesel exhaust was also a frequent exposure for the machinists, locomotive engineers and other workers.

Other causes include exposure to ammonia and herbicides, agricultural chemicals, and mercury. Myelodysplastic Syndrome has also been associated with chemotherapy and radiation. Treatment options for MDS are limited, however a stem cell transplant is efficient in a lot of cases. During this procedure, stem cells taken from the bone blood or marrow are removed and then reinfused back into the body. Stem cells are transformed into blood cells and replace those that have been damaged by radiation or chemotherapy.

Diagnosis

If a person is diagnosed with MDS or MDS, he/she will have abnormal blood cells found in bone marrow. Bone Marrow, the soft tissue within bones, is the place where new blood cells are made. MDS causes bone marrow cells to produce abnormal stem cells, which block normal cells. This causes the body to not having enough healthy blood cells. Each type of MDS has its own specific symptoms.

These include weakness, fatigue and frequent infections. MDS may progress to leukemia.

Talk to our railroad accident attorneys about the possibility of filing claims for FELA compensation claim for you or a loved one who was diagnosed with Myelodysplastic Syndrome injury settlements syndrome as a result exposure to benzene or diesel fumes while working. FELA is a federal law that allows railroad employees to make claims for injuries they suffered at work.

The lawyers at Sullivan & Associates are highly adept in railroad accident and wrongful death cases. Contact us today to schedule an initial consultation for free. We represent clients across the across the country. Our firm is licensed in Florida and California. We have offices in Jacksonville, Orlando Fort Lauderdale, Miami and Tampa, in addition to other cities. We also offer our clients via videoconference and telephone.

Treatment

In MDS, the blood-forming cells of your bone marrow become abnormal. In the result, you may experience a decrease of the types of blood cells that carry oxygen and fight infection (red blood cells) and help your body create healthy blood clots (platelets) or control bleeding.

Different types of MDS have different diagnosis and treatment options. The diagnosis of these diseases is made by your doctor based on blood and bone marrow tests.

Three out of three patients develop acute myeloid lymphoma (AML). AML is a tumor that begins in the bone marrow. If your MDS is not treated, it could progress to aml myelodysplastic syndrome.

An immunocytochemistry test is used to detect antigens in samples of your bone marrow. Antibodies are linked to an enzyme or a fluorescent dye. When antibodies are bound to an antigen in your sample, the antibody dye complex is visible under a microscope. The type of antigen identified aids doctors in determining if the bone marrow is affected and Myelodysplastic Syndrome Mds also what type of MDS you suffer from.

The standard of care for MDS is a variety of chemotherapy drugs. These include methotrexate and fludarabine, azacitidine, and decitabine. Inqovi, a tablet-form drug has been proven to increase survival rates for certain MDS patients, and reduce the need for transfusions. Our railroad injury attorneys can assist you in understanding your legal and medical options.