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Acute Lymphocytic Leukemia

Acute lymphocyticleukemia (ALL) is a rare malignancy which develops from abnormal lymphoid stem cells. Leukemia of this type can affect T and B cell types and can cause a variety of symptoms depending on the cell type is affected.

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What is Acute Lymphoblastic Leukemia (ALL)?

Acute lymphoblastic leukemia (ALL) is also known as acute leukemia is a cancer that affects blood as well as the bone marrow - which is the bone marrow's spongy tissues in which blood cells develop. The cancer causes too many mature white blood cells (blast cells) to be created in the bone marrow. These blast cells crowd healthy blood-forming cell and disrupt their normal function. There are two kinds of ALL including B cell and T-cell. These are further subdivided based on which blood-forming cells are affected. B cell ALL is the most common form of ALL and is most commonly seen in children.

Most cases of ALL start in the bone marrow, but it may also start in other tissues such as the liver, spleen and the central nervous system (brain and the spinal cord in men) or testicles (in males). It is a problem that affects adults and children of all ages, but is more common among younger people.

It's not clear what triggers the mutations in DNA that can lead to leukemia. Certain factors can increase your risk of leukemia. These include:

Other potential risks include exposure to radiation, certain genetic disorders like Down syndrome, or prior radiotherapy or chemotherapy for another condition. If you notice any symptoms or signs that may indicate leukemia, it's crucial to talk to your doctor immediately. These symptoms could be a sign of flu.

Signs and Symptoms

Acute lymphoblastic Leukemia (ALL) begins in immature blood cells in the bone marrow, which is the hollow center inside your bones where blood is created. The cancerous cells increase in size and rapidly spread, taking over the space where normal blood cells ought to be. This stops your body from producing enough healthy blood to fight infections, control bleeding and provide oxygen to all the cells in your body.

Adult ALL can cause fatigue, fever, easy bruising, bleeding, weight loss and a feeling of being full in the stomach or in bones. Your doctor can diagnose ALL by performing tests of bone marrow and Canadian Pacific Colon Cancer blood, such as an entire cell count (CBC) and canadian Pacific non hodgkins lymphoma electrolyte level, as well as an LDH test. Imaging tests, like X-rays and CT scans may be ordered to determine if the cancer has spread. Your doctor may also order an insertion of the spinal cord (also known as a lumbar puncture) to get samples of the fluid surrounding your spinal cord in order to check for leukemia cells in your spinal fluid.

Some people with ALL do not show any symptoms or signs. They can only be diagnosed through bone marrow or Canadian Pacific Non Hodgkins Lymphoma blood test. Some people experience mild or moderate symptoms like fatigue and fevers, bruising and bleeding. On this page, you can find out more about the forms and survival rates of leukemia.

Diagnosis

Acute lymphocyticleukemia can be diagnosed when a patient has a low number of healthy blood cells (hemoglobin, red blood cell and platelet counts). It usually starts in the bone marrow, which is the hollow center inside bones where blood is made. Cancer cells multiply rapidly because they do not function as normal blood cells. They also deplete healthy cells, preventing them from performing their duties. This can lead to problems with breathing and other organs.

Doctors may observe that children who are always tired or having difficulty breathing. They will collect a sample of blood to determine whether there are a lot of healthy cells. This is called a complete count of blood (CBC). The blood sample is examined for the presence of chemicals that aid the production of white blood cells to combat infection. They also look for a genetic abnormality in the cells called a Philadelphia Chromosome. This can identify patients who may benefit from targeted therapy that is designed for their particular type of leukemia.

Other tests include the use of a spinal tap or lumbar puncture. This test is designed to check the for the presence of fluid around the spinal cord for leukemia cells. Sometimes, it is performed prior to a transplant to prevent leukemia. The use of radiation therapy is usually before the transplant of stem cells to prepare the body for it.

Treatment

Acute lymphoblastic tumor is treated by chemotherapy, which involves the use of medications to destroy cancerous cells. This includes cytotoxic agents that kill cancer cells and normal cells they come into contact with. Additionally, it includes immunotherapy that helps to strengthen the immune system. Other treatments include radiation therapy and stem cell transplantation.

In addition, there are a number of other treatments that can increase the chances of survival for those suffering from ALL. These include targeted therapies, immunotherapy, and other medications designed to help manage the canadian pacific chronic obstructive pulmonary disease or ease symptoms. These treatments can be utilized in conjunction with other forms of treatment, based on a person's needs.

This PDQ cancer information summary for health professionals gives extensive, peer-reviewed and Canadian pacific throat cancer evidence-based information regarding the treatment of adult acute lymphoblastic Leukemia (ALL). It is designed to help healthcare professionals make clinical decisions. It doesn't contain formal guidelines or treatment guidelines and is not meant to replace the advice given by your doctor or any other healthcare professional.

Acute lymphoblastic canadian pacific leukemia is a type of cancer that affects the blood-forming tissues, like the lymph nodes as well as bone marrow. The cancer is caused by an overgrowth of lymphoblasts either in bone marrow, or blood. These lymphoblasts are immature cells that usually transform into white blood cells, red blood cells, and platelets. This excess production leaves less space for healthy red blood cells, which can cause anemia. It also leaves less space for healthy white blood cells, which may cause infection and bleeding problems.